GameTrailers went on a tour of Los Angeles to compare the real city streets to that of Grand Theft Auto V's Los Santos. The video tour focuses on the big touristy spots around Santa Monica, with some glimpses at Hollywood too.
So how do the two compare? Pretty close for the most part. Santa Monica pier isn't as lively in Los Santos as in real life,
via destructoid http://www.destructoid.com/how-does-gta-v-s-los-santos-compare-to-los-angeles--262546.phtml