It's been confirmed that all enemies and items will be randomized during each playthrough to maximize replayability. This seems like not just a good idea to maxmize game time, but a good way to maximize scares and tension.
via N4G: pc news feed http://n4g.com/news/1174761/random-enemies-and-items-in-re-revelations-are-randomly-placed
via N4G: pc news feed http://n4g.com/news/1174761/random-enemies-and-items-in-re-revelations-are-randomly-placed